Easy money for lims. Now Singapore gomen also want ?

Will she be paying the million in ringgit or SGD?

Many countries which wouldn't sign ICERD and Rome Stature, yet want to bring Israel to iCC

Mad-hat-dick?

After sad sad-dick, who's next? Wan saifool? Hardy awang? Moodin?

While pmx is too occupied with foreign country issue, the opposition block is engineering Sheraton Move 2.0; and Sabahans & we Sarawakians are pushing for independence......

Weird thing. Some argue that the gomen has not been fair to the society as only the rich children seem to master english by attending the private and international schools, while the poor got stucked with BM. Totally no brainers. The kampung folks i .e. parents of the poor children, have sealed the fate for their children or otherwise wouldn't have voted in the ultra malay tp govern them

That's why his rating falls when his gets himself surrounded by a bunch of pak pandir with qualifications from papermills

And the first thing pmx did was to embark on a series of costly (yet later will be proven to be futile) foreign trips and to try to get investment and support from the global economy giants. Futile because next make his voice was heard on the international stage for being on the antagonising side of the middle east crisis, potentially inviting critical sanction and retribution. Hence futile futile futile

In msia, politicians continue to enjoy their lives as T20 by grabbing the best part of the pie, rain or shine. So they can comment on foreign war issues even in a way that will bring down the country reputation, deepen economy crisis, hyperinflation and greater suffering to the ignorant ppl. Singapore got thoughtful leaders, hence cleverer citizens too

Singapore has taken the best measure to ensure its people's well-being is protected. Publicly displaying or wearing foreign national emblems relating to the Israel-Hamas war without a permit is an offence

Quote: "Starting something of this magnitude and unable to finish is a suicide mission..."

These ppl think this is an alternative way to get to heaven

I am not impressed with Palpatine's SG4. I have suggested 3S for so long. Singapore-Sarawak-Sabah. Singapore got world class cabinet, education and finance status, but no land as well as lacking in human capital and natural resources. We have land, ppl and natural resources - abundance. Win-win for sure

In a recent development, schools in Sabah and Sarawak have received word from their respective state governments that participation in the solidarity week program is now optional. Interestingly, the heads of mission schools have taken an even bolder stance by declaring their intent to disregard this directive. It's worth noting that the coalitions governing these two states are significant players in the overarching unity government.

On a separate note, Sarawak has boldly rejected a recent warning from Anwar, issued just last week, which stated that any communication with government departments in languages other than Malay would not be considered. This stands as a testament to the complex dynamics and diverse linguistic landscape in the region.

In a recent development, schools in Sabah and Sarawak have received word from their respective state governments that participation in the solidarity week program is now optional. Interestingly, the heads of mission schools have taken an even bolder stance by declaring their intent to disregard this directive. It's worth noting that the coalitions governing these two states are significant players in the overarching unity government.

On a separate note, Sarawak has boldly rejected a recent warning from Anwar, issued just last week, which stated that any communication with government departments in languages other than Malay would not be considered. This stands as a testament to the complex dynamics and diverse linguistic landscape in the region.

Betul. Penis-sular Ada Alibaba and 40 thieves.

Quote: "Singapore buys most of their weapons from Israel..."

Yes, "only from the best" we buy or learn

As a native tribe member in Sarawak, I genuinely (and have not problem to) admire the Chinese and Indian for defending to live as their unique selves any where they go. But I got no respect for those who turn their back & abandon their original roots and living values, and try to be copycat version of some distant past cult of distant nation(s). I have always teach all my children, grand children and great grand children this: "Born original, stay original. Do NOT live & die as copycat"


DickyMe

13,771 posts

Posted by DickyMe > 2 months ago | Report Abuse

""Born original, stay original. "
Exactly my thought!
Don't cheat yourself!

As a native tribe member in Sarawak, I genuinely (and have not problem to) admire the Chinese and Indian for defending to live as their unique selves any where they go. But I got no respect for those who turn their back & abandon their original roots and living values, and try to be copycat version of some distant past cult of distant nation(s). I have always teach all my children, grand children and great grand children this: "Born original, stay original. Do NOT live & die as copycat"


DickyMe

13,771 posts

Posted by DickyMe > 2 months ago | Report Abuse

""Born original, stay original. "
Exactly my thought!
Don't cheat yourself!

Nuke war follows Sun Tze - finish war fast!

I am not impressed with Palpatine's SG4. I have suggested 3S for so long. Singapore-Sarawak-Sabah. Singapore got world class cabinet, education and finance status, but no land as well as lacking in human capital and natural resources. We have land, ppl and natural resources - abundance. Win-win for sure

The current slogan is "Rights to defend own country". Previously was "Weapon of mass destruction" - to attack Iraq.

Quote: "qqq3 is daydreaming of medieval times and forget that Israel has nuclear bomb and can nuke Arabs into dust."

Not good enough. That's why USA is making one with 24 times the power.

Exactly. Anyone can argue one way or the other. History of the middle east was packed with genocidal crimes

Cannot compare orange and apple. With MA1963, we set to be secular and will overtake u guys in penis-sular sooner or later in progress.

Do not be narrow minded. Depopulation may not be entire bad. Got pros and cons

1. Hamass fighters camouflage well among the civilians

We Sarawakians very fed up with 100% nonperforming pseudoreformist ai who wouldn't open his mouth to tell off those deluded baddies

Baddies are those who learn but don't want to tell the truth about superfood called pork

Nostradamus': "Those monotheistic religions have been tangled in endless wars since their very beginning. Blood all over their inventors' hands"

NB.Why school children must learn and understand history text.......

Nostradamus: "The third big war will begin when the big city near Jerusalem is burning."

As prophesized by Nostradamus : "Come year 2023, ..................."

Scientifically, pork is the best meat for children's brain to grow optimally

What life values that children learn in: 1. Fairness vs discrimination 2. Honesty vs crime of soalan bocor (ketidakjujuran) 3. Truthfulness vs manipulation ( tipu-tipu menang pertandingan) 4. Meritocracy & the meaning of you reap what you sow vs kulitocracy & heaven is only for specified delusion 4.

In the context of WW3, which group of people is most likely to be significantly impacted or affected?

A. Individuals with a strong genetic predisposition towards skepticism regarding belief in deities.

B. Those who possess genetic tendencies towards extreme religious fanaticism.

C. People who remain neutral and don't strongly lean towards atheism or religiosity.

We are more progressive, future looking and open minded. Next we plan to launch state wide all school level solidarity against Christians who are discriminated from using the word alllla hh

Time wasters & real distraction from discussing matters that relate to the well fare of the rakyat. Issues on excessive vaccine procurement, flawful ventilator purchase, etc etc

Caliph Yemen, Caliph Hezbollah & Caliph Hamass deserve heaven and full respect. Others are cowards (including paspuspis & gang)

Exactly. He doesn't know his supporters and voters. Bagai kacang lupakan kulit. How he won the election............

Stop making a fuss on this matter. No action talk talk talk only lah nobita. Let us Sarawakians with full autonomy in education show you the real meaning to move forward

QUote: "qqq47660 > 6 minutes ago | Report Abuse

sted by qqq47660 > 1 second ago | Report Abuse

Yes, Caliph Yemen & Caliph Hamass deserve heaven and full respect. Others are cowards
==========


next hezbollah will declare war on Israel................expect escalation and no return to pre Oct 7."

Yes, Caliph Yemen, Caliph Hezbollah & Caliph Hamass deserve heaven and full respect. Others are cowards (including paspuspis & gang)

Quote: "qqq47660 > 15 hours ago | Report Abuse

d Hama is the representation of Muslim and Arab hearts and minds"

Yes, Caliph Yemen & Caliph Hamass deserve heaven and full respect. Others are cowards

HUAT ARRRRRRRRRRRR

Above are 3 key tips from someone who lives over 100 years and still feel like living in his tweenish era (it's me)

3. Declutter your heart cells (cardiomyocytes) by the EP program

The accumulation of glycated end products and amyloid in cells can have detrimental effects on various organs, including the heart. Autophagy, a cellular process responsible for degrading and recycling cellular components, can play a crucial role in reducing the risk of heart attack, aging-related cardiac issues, and heart failure by clearing these harmful substances.
Reduction of Oxidative Stress:
• Glycated end products and amyloid can lead to increased oxidative stress within cells. This oxidative stress can damage cellular components, including proteins, lipids, and DNA, and contribute to inflammation and aging of the heart.
• Autophagy helps to clear damaged cellular components, reducing oxidative stress and mitigating the detrimental effects on cardiac tissues.

Maintenance of Protein Quality:
• Autophagy plays a critical role in maintaining protein quality within cells. It identifies and selectively degrades misfolded, damaged, or aggregated proteins, such as amyloid.
• In the context of the heart, the clearance of amyloid can prevent the formation of toxic protein aggregates, which are often associated with cardiac diseases, such as amyloid cardiomyopathy.

Energy Homeostasis:
• Autophagy is involved in maintaining energy balance by recycling cellular components and providing nutrients when needed.
• Dysregulation of energy metabolism is linked to heart diseases, including heart failure. By efficiently recycling cellular components, autophagy can contribute to energy homeostasis in the heart.

Cardiomyocyte Health:
• Cardiomyocytes are the specialized muscle cells of the heart responsible for its contraction. Accumulation of glycated end products and amyloid within cardiomyocytes can impair their function.
• Autophagy helps clear damaged organelles and proteins from cardiomyocytes, preserving their health and function and reducing the risk of heart failure.

Prevention of Inflammation:
• Accumulated glycated end products and amyloid can trigger inflammation, which can damage heart tissues and promote the progression of atherosclerosis and plaque formation.
• Autophagy can limit inflammation by removing the triggers, thereby reducing the risk of heart attack and atherosclerosis.

Slowing Down Aging-Related Cardiac Changes:
• Aging is a major risk factor for heart diseases. Accumulation of damaged proteins and cellular components accelerates aging-related cardiac changes.
• Autophagy can slow down these aging-related changes by maintaining cellular homeostasis, reducing oxidative stress, and preserving the integrity of cardiac cells.

Reduction of Ischemia/Reperfusion Injury:
• Autophagy can also protect the heart during episodes of ischemia and reperfusion, which are associated with heart attacks. It helps clear damaged components and reduces the risk of cell death during these events.

2. Normalising hsCRP

High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation in the body. It is produced by the liver and released into the bloodstream in response to inflammation or infection. hsCRP levels are often measured to assess the degree of inflammation within the body, and they can be useful in various medical contexts, including the evaluation of risk factors for cardiovascular diseases like ischemic heart disease (IHD).
Inflammation and Ischemic Heart Disease (IHD): Ischemic heart disease, also known as coronary artery disease (CAD) or coronary heart disease (CHD), is a condition characterized by the narrowing of the coronary arteries that supply blood to the heart muscle. This narrowing is often due to the buildup of fatty deposits (atherosclerosis) in the arterial walls. IHD can lead to reduced blood flow to the heart, which may result in chest pain (angina) or, in severe cases, heart attacks (myocardial infarctions).
In recent years, research has indicated that inflammation plays a significant role in the development and progression of IHD. Chronic, low-level inflammation can contribute to the formation of atherosclerotic plaques in the coronary arteries. Inflammatory processes within the arterial walls can lead to the rupture of these plaques, triggering blood clot formation, and subsequently blocking blood flow, resulting in a heart attack.

hsCRP is a sensitive marker of systemic inflammation. Elevated hsCRP levels in the blood indicate ongoing inflammation in the body, even at low levels not typically detected by the standard CRP test. When hsCRP levels are high, it suggests that inflammation is present in the body.

The Evolutionary Origin of Autoimmune basis for Diseases, Mediated by Shared Last Universal Common Ancestor Antigens, Explains Molecular Mimicry and Autoantibodies Cross-Reactivity to Prevent Systemic Inflammation Leading to Damage to Insulin Receptors, Accelerated Atherosclerosis, and Ischemic Heart Disease.
Autoimmune diseases involve the immune system mistakenly attacking healthy cells and tissues in the body, leading to a range of disorders. While the causes of autoimmune diseases are complex and multifactorial, shared antigens from the Last Universal Common Ancestor (LUCA) may have contributed to these conditions, particularly in the context of insulin resistance due to damages to the insulin receptors, inflammation-mediated accelerated atherosclerosis, and ischemic heart disease.
The LUCA is the hypothetical common ancestor of all life on Earth and dates back billions of years. While LUCA and human evolution are separated by vast time scales, it's possible that common antigenic elements were conserved throughout evolution. This shared antigenic heritage may contribute to molecular mimicry and cross-reactivity in the immune system.

Molecular mimicry is a phenomenon where pathogens or foreign antigens share structural similarities with self-antigens, potentially leading to cross-reactivity. Over time, the human immune system has developed to recognize and respond to pathogens, some of which may have antigens resembling self-antigens. This mimicry can trigger the production of autoantibodies that mistakenly target self-antigens.

Systemic inflammation resulting from autoimmune responses can damage various tissues and organs, including insulin receptors, which play a crucial role in regulating blood glucose levels and preventing diabetes mellitus. By linking the origins of autoimmune diseases to shared LUCA antigens, this hypothesis suggests that understanding the evolutionary context of autoimmunity may provide insights into mechanisms to prevent systemic inflammation and subsequent damage to insulin receptors.

Low-grade systemic inflammation is also associated with accelerated atherosclerosis, a condition characterized by the buildup of plaque in arteries, and ischemic heart disease, which can result from reduced blood flow to the heart muscle. By better understanding the evolutionary basis of autoimmune diseases, we may uncover ways to mitigate the inflammation that contributes to atherosclerosis and ischemic heart disease.

Tips:

1. Reverse aging vessels

Understanding evolution to reverse aging by activating the SIR gene and optimizing individualized stress exposure and endurance is a comprehensive approach that has the potential to reduce the risk of cancer, heart disease, and promote longevity.

Evolutionary Insights: Evolutionary biology offers us insights into how our genes, including the SIR gene, have evolved over time to protect our species and ensure our survival. By understanding the genetic and cellular mechanisms that have evolved to maintain health and longevity, we can leverage this knowledge to address aging-related health issues.

Aging and Disease Risk: Aging is a significant factor in the development of many chronic diseases, including cancer and heart disease. As we age, our cells accumulate damage, and our body's repair mechanisms become less efficient. The SIR gene is associated with DNA repair and maintaining cellular health, making it a critical target for interventions.

Individualized Stress Exposure: Stress, when properly managed, can stimulate adaptive responses in the body. Individualized stress exposure acknowledges that the optimal level and type of stress may vary from person to person. By identifying an individual's stress threshold, we can design interventions that promote health and longevity while minimizing harm.

Cancer Risk Reduction: Individualized stress exposure and the activation of the SIR gene can potentially reduce cancer risk. Chronic stress and cellular damage are risk factors for cancer. By optimizing stress exposure and enhancing DNA repair, we can lower the likelihood of mutations that lead to cancer development.

Heart Disease Risk Reduction: Heart disease is closely linked to the aging process. By promoting cellular repair and health through SIR gene activation, we can mitigate the age-related factors that contribute to heart disease. Proper stress management and endurance training can also improve cardiovascular health.

Longevity and Healthy Aging: The ultimate goal is to extend human lifespan and promote healthy aging. By activating the SIR gene, reducing cellular damage, and optimizing stress exposure, we aim to slow down the aging process and maintain health and vitality into old age.

EngineeringProfit

15,869 posts

Posted by EngineeringProfit > 0 seconds ago | Report Abuse

2. The Evolutionary Origin of Autoimmune basis for Diseases, Mediated by Shared Last Universal Common Ancestor Antigens, Explains Molecular Mimicry and Autoantibodies Cross-Reactivity to Prevent Systemic Inflammation Leading to Damage to Insulin Receptors, Accelerated Atherosclerosis, and Ischemic Heart Disease.
Autoimmune diseases involve the immune system mistakenly attacking healthy cells and tissues in the body, leading to a range of disorders. While the causes of autoimmune diseases are complex and multifactorial, shared antigens from the Last Universal Common Ancestor (LUCA) may have contributed to these conditions, particularly in the context of insulin resistance due to damages to the insulin receptors, inflammation-mediated accelerated atherosclerosis, and ischemic heart disease.
The LUCA is the hypothetical common ancestor of all life on Earth and dates back billions of years. While LUCA and human evolution are separated by vast time scales, it's possible that common antigenic elements were conserved throughout evolution. This shared antigenic heritage may contribute to molecular mimicry and cross-reactivity in the immune system.

Molecular mimicry is a phenomenon where pathogens or foreign antigens share structural similarities with self-antigens, potentially leading to cross-reactivity. Over time, the human immune system has developed to recognize and respond to pathogens, some of which may have antigens resembling self-antigens. This mimicry can trigger the production of autoantibodies that mistakenly target self-antigens.

Systemic inflammation resulting from autoimmune responses can damage various tissues and organs, including insulin receptors, which play a crucial role in regulating blood glucose levels and preventing diabetes mellitus. By linking the origins of autoimmune diseases to shared LUCA antigens, this hypothesis suggests that understanding the evolutionary context of autoimmunity may provide insights into mechanisms to prevent systemic inflammation and subsequent damage to insulin receptors.

Low-grade systemic inflammation is also associated with accelerated atherosclerosis, a condition characterized by the buildup of plaque in arteries, and ischemic heart disease, which can result from reduced blood flow to the heart muscle. By better understanding the evolutionary basis of autoimmune diseases, we may uncover ways to mitigate the inflammation that contributes to atherosclerosis and ischemic heart disease.

Tips:

1. Reverse aging vessels

Understanding evolution to reverse aging by activating the SIR gene and optimizing individualized stress exposure and endurance is a comprehensive approach that has the potential to reduce the risk of cancer, heart disease, and promote longevity.

Evolutionary Insights: Evolutionary biology offers us insights into how our genes, including the SIR gene, have evolved over time to protect our species and ensure our survival. By understanding the genetic and cellular mechanisms that have evolved to maintain health and longevity, we can leverage this knowledge to address aging-related health issues.

Aging and Disease Risk: Aging is a significant factor in the development of many chronic diseases, including cancer and heart disease. As we age, our cells accumulate damage, and our body's repair mechanisms become less efficient. The SIR gene is associated with DNA repair and maintaining cellular health, making it a critical target for interventions.

Individualized Stress Exposure: Stress, when properly managed, can stimulate adaptive responses in the body. Individualized stress exposure acknowledges that the optimal level and type of stress may vary from person to person. By identifying an individual's stress threshold, we can design interventions that promote health and longevity while minimizing harm.

Cancer Risk Reduction: Individualized stress exposure and the activation of the SIR gene can potentially reduce cancer risk. Chronic stress and cellular damage are risk factors for cancer. By optimizing stress exposure and enhancing DNA repair, we can lower the likelihood of mutations that lead to cancer development.

Heart Disease Risk Reduction: Heart disease is closely linked to the aging process. By promoting cellular repair and health through SIR gene activation, we can mitigate the age-related factors that contribute to heart disease. Proper stress management and endurance training can also improve cardiovascular health.

Longevity and Healthy Aging: The ultimate goal is to extend human lifespan and promote healthy aging. By activating the SIR gene, reducing cellular damage, and optimizing stress exposure, we aim to slow down the aging process and maintain health and vitality into old age.

Belum belajar berdikari dan menyara hidup, sudah diajar demonstrasi dan memegang senjata bertempur

Great distraction! When the school children are busy to focus on foreign conflicts afar, they couldn't protest against inflation, depreciation of ringgit and misappropriation of public fund at the same time.